Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...
Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy
RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback.
MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...
How the hydrolytic activity of mitochondrial ATP synthase is modulated during brown adipose tissue (BAT) thermogenesis ...
A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...
K Heran Darwin is at New York University Grossman School of Medicine and a regular columnist for EMBO reports.
Metabolic rewiring is essential for osteoclast differentiation and bone resorption. This study shows that glutaminolysis ...
Human papillomavirus (HPV) and hyperactivated YAP1 form a YAP1-HPV oncogenic alliance to drive the malignant transformation ...
Changing nutrient environments challenge cells as they affect both protein biosynthesis and cell cycle length. This work ...
Co-expressing NPY and its inhibitory receptor Y2 in excitatory hippocampal cells allows inhibitory autoregulation of ...
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