The Chicago White Sox (36-117) open a three-game series against the San Diego Padres (87-66) with a Friday meeting at PETCO ...

Tuesday night's game between the San Diego Padres and Houston Astros was in an instant classic. It had everything needed to make it one of the best games played ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

A prominent MLB insider believes both the San Diego Padres and Baltimore Orioles could target the top slugger in free agency this winter.

The Padres look postseason-ready. Dylan Cease looks Game 1 ready. And the San Diego offense looks ready to mash against just ...

As of now, he has accumulated a total of 1,994 strikeouts at the MLB level and previously recorded 1,250 strikeouts in ...

The first Soto trade might have backfired, but the second is proving to be one of the better moves the Padres have made in ...

San Diego Padres ace Yu Darvish might have been sidelined for much of the season due to injuries and a personal matter, but ...

I think it was $13, and I was throwing beers to Padre fans." After 20 years of road trips the Welborns had seen the Padres ...

The San Diego Padres have been the best team in baseball since the All-Star break, blazing a trail toward the playoffs to the ...

The two-time batting champ went 141 plate appearances without a strikeout. The Astros' Spencer Arrighetti ended the streak.

Yordan Alvarez and Jurickson Profar are among the players with prop bets for the taking when the Houston Astros and the San ...